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Organ Transplant

Articles and resources for Organ Transplant in Transplant Surgery.

Organ transplant is a medical procedure where a failing or damaged organ is replaced with a healthy one from a donor. Common reasons for considering a transplant include severe organ failure due to conditions like chronic kidney disease, heart disease, liver cirrhosis, or lung disorders. Patients may undergo extensive evaluations to determine their suitability for transplantation, including tests to assess their overall health and the compatibility of the donor organ.

The transplant procedure typically involves surgical removal of the diseased organ and the careful placement of the donor organ. Surgeons perform this operation in a specialized setting, ensuring that the patient is under anesthesia for comfort. After the transplant, patients usually stay in the hospital for monitoring and recovery, which may involve managing medications to prevent organ rejection and support healing.

While organ transplants can significantly improve quality of life and longevity, they also come with potential risks. Benefits may include restored organ function and improved overall health, allowing individuals to return to daily activities. However, risks can include complications from surgery, the possibility of organ rejection, and side effects from immunosuppressive medications. Each patient’s situation is unique, and outcomes can vary based on numerous factors.

Anesthesia Management for Patients Undergoing Organ Transplants

This research paper discusses how to best manage anesthesia in patients undergoing solid organ or reconstructive transplants. The authors focus on specific factors such as reperfusion (restoring blood...

C. Difficile Infection Risks and Treatments for Organ Transplant

This research paper is about a type of infection called Clostridium difficile (C. difficile) that often affects people who have had a solid organ transplant. This kind of infection is common and can l...

Combined Liver and Chest Organ Transplants: What Patients Should Know

This research paper discusses a medical procedure where a chest organ (like the heart or lungs) and the liver are transplanted together in patients who have two failing organs. This operation is done ...

Exploring the Potential of Pig-to-Human Organ Transplants

The research paper discusses the recent progress in the field of organ transplantation that could potentially solve the issue of organ shortage. This refers to the scarcity of organ donors compared to...

Immune Checkpoint Inhibitors and Organ Transplant Rejection Risks

This research aimed to investigate whether a certain type of cancer treatment, known as immune checkpoint inhibitors (ICIs), could lead to transplant rejection in patients who have received organ tran...

Impact of Notto on Organ Donation and Transplantation in India

This study looks at the impact of the National Organ and Tissue Transplant Organization (NOTTO) on organ donation and transplantation in India. The analysis of data from 2013 to 2018 shows that the cr...

Impact of Organ Availability on Kidney Transplant Utilization in the

This study looks at how competition and the availability of organs for transplant affect the use of kidneys in the United States. The researchers divided the areas studied into four groups depending o...

Improving Kidney and Liver Transplants with Hypothermic Perfusion

This research paper discusses a study conducted on the effects of a process called hypothermic oxygenated machine perfusion in kidney and liver transplants. This method involves keeping donated organs...

Improving Organ Preservation for Transplant Surgery Using Pigs

This research paper is about improving how we preserve organs for transplantation surgery. In the past, we've stuck to a traditional method called cold static storage (CS), which is great for organs t...

Improving Organ Transplant Success with Nanoparticle Drug Delivery

This research paper presents a new method to help improve the success of organ transplants. When an organ is removed from a donor, it often experiences inflammation. This inflammation can cause the re...

Improving Organ Transplant Success with Optical Biomarkers for Liver

This research paper discusses the challenges and opportunities in using optical biomarkers for solid-organ transplants, specifically focusing on the liver. The process of transplanting organs is compl...

Improving Organ Transplants with Normothermic Perfusion Techniques

This research paper discusses two methods used to preserve and transport organs for transplants: normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP). These methods can help ...

Improving Testing Strategies for Solid Organ Transplant Patients

The research paper explores the concept of diagnostic stewardship, or the careful management of medical testing, in patients who have received solid organ transplants. These patients are often at risk...

Increasing Organ Transplants: the Optn's New Strategy for Success

This research paper discusses the formation of the Expeditions Task Force (ETF) by the Organ Procurement and Transplant Network (OPTN) in the United States. The ETF's goal is to significantly increase...

Infection Risks and Prevention After Solid Organ Transplant Surgery

This research paper is about the risks of infection in patients who have received a solid organ transplant (SOT). These types of patients are prone to infection due to several factors, including the c...

Innovative Approaches to Improve Organ Transplant Success Rates

This research paper discusses the ongoing issues with organ transplants, mainly the shortage of available organs and the body's tendency to reject transplanted organs. The researchers note that curren...

Innovative Treatments for Organ Transplant Patients: Reducing

The research paper discusses how organ transplant recipients need carefully designed treatment plans to reduce the risk of their body rejecting the organ and to lower the chance of death. Traditional ...

Kidney Transplant Survival Rates: Insights for Patients and Families

This research paper looked at the survival rates of patients who received kidney transplants. Their study was based on data from the United Network for Organ Sharing (UNOS), which was collected betwee...

Maximizing Organ Donation: Effective Use of Deceased Donor Organs

This research paper discusses the importance of using donated organs from deceased donors more effectively, both in the UK and globally. It suggests that a detailed understanding of how best to use ea...

Motivational Interviewing for Teens Undergoing Organ Transplant

This study discusses the use of Motivational Interviewing (MI), a technique often used to help people change their behaviors, in adolescents undergoing organ transplants. Teenagers often struggle with...

Nanoparticle Treatments for Improving Organ Transplant Success

The use of nanoparticles (tiny particles) to deliver drugs to specific parts of the body is a promising method that can make treatments more effective and reduce side effects. This technique can be us...

Neurological Complications After Organ Transplant: What Patients Need

This research paper examines the neurological complications that can arise in patients who have received solid organ transplants. Around one third of these patients will experience neurological sympto...

New Gene Panel Improves Detection of Heart Transplant Rejection

The research paper discusses a challenge in diagnosing heart transplant rejection based on genetic analysis. The existing method, which involves a comprehensive analysis of all the genes in the body (...

New Tool Predicts Kidney Transplant Rejection Using Gene Analysis

This research paper is about creating a diagnostic tool that analyzes gene expression in kidney transplant biopsies. The goal is to predict and classify types of kidney transplant rejection, such as n...

Non-Invasive Urine Test for Early Detection of Organ Rejection

This research studied a new, non-invasive way to detect problems after an organ transplant. Specifically, it looked at small particles in urine (known as urinary extracellular vesicles or UEVs) to ide...

Ongoing Care for Adult Patients After Solid Organ Transplant

This research paper discusses the importance of ongoing care for patients who have received a solid organ transplant (SOT) such as a heart, kidney, liver, or lung. Organ transplantation is a significa...

Pediatric Organ Transplants: Liver and Kidney Solutions for Children

This research paper explains that liver and kidney transplants are now the typical treatment for children with severe liver and kidney disease. Since the first successful kidney transplant in 1954, an...

Pregnancy After Organ Transplant: Risks and Considerations for Women

This research paper discusses the complexities and risks involved when a woman who has received a solid organ transplant becomes pregnant. There is very little information available about this topic, ...

Progress and Challenges in Kidney Transplants in Denmark

This research paper is about the progress and challenges in kidney transplants since the first operation was done in Denmark in 1964. Since then, nearly 10,000 such procedures have been done. In the l...

Safe Organ Transplants From Sars-Cov-2 Positive Donors Explained

This research paper looks at the risk of transferring the SARS-CoV-2 virus (the virus that causes COVID-19) through organ transplants. The researchers examined cases where individuals who did not have...

The Evolution of Organ Transplantation in Israel: a Historical

This paper discusses the history and progress of organ transplantation in Israel. Organ transplants started in the mid-20th century, with improvements in surgical techniques, understanding of immune r...

Understanding Abo-Incompatible Kidney Transplants and Accommodation

This research paper discusses the concept of accommodation in the realm of organ transplants, particularly kidney transplants. Accommodation is a phenomenon where a transplanted organ, despite not mat...

Understanding Acceptance of Intervention Organs for Kidney Transplants

This research paper is about how willing people waiting for a kidney transplant are to accept an "intervention organ," or an organ that has been a part of some medical research. The researchers presen...

Understanding Donor-Transmitted Cancer Risks in Organ Transplants

This research paper examines the issue of cancer being transmitted from organ donors to recipients, an occurrence which can have major consequences for both the patient and other individuals who have ...

Understanding Geographic Disparities in Organ Transplant Access

This research paper is about the inequality in organ transplantation availability depending on where patients live. Despite rules stating that location should not affect a person's chance of receiving...

Understanding Il-18's Role in Organ Transplant Success and Rejection

This research paper looks into the role of a specific protein, IL-18, and its receptor (IL-18R) in organ transplantation. IL-18 and IL-18R help regulate our body's immune responses, which is crucial d...

Understanding Immunosuppressants in Organ Transplant Surgery

This research paper discusses the use of drugs that suppress the immune system, known as immunosuppressants, during the transplantation period. These drugs are generally used before and after transpla...

Understanding Kidney Transplant Rejection: Key Factors for Patients

This research looked at chronic active antibody-mediated rejection (CAMR), a condition that can occur after kidney transplant and lead to the failure of the transplanted organ. The scientists used a t...

Understanding Liver Transplant Risks with Older Donors for Patients

This study looks at the outcomes of liver transplants from older donors. It found that the age of the donor is a risk factor for the new liver not working properly a year after the transplant. The stu...

Understanding Once-Daily Tacrolimus for Organ Transplant Patients

Tacrolimus is a crucial drug used to prevent the body from rejecting a transplanted organ. The original version, Prograf®, is taken twice a day. To make it easier for patients to remember to take thei...

Understanding Opportunistic Infections After Organ Transplant Surgery

This research paper discusses the issue of infections after organ transplants. In 2017, there were 34,770 organ transplants performed in the U.S. Although these surgeries are generally successful, the...

Understanding Organ Transplant Rejection: Key Insights for Patients

This research paper examines how our bodies reject organ transplants at a molecular level. Researchers can get the best understanding of this by looking at the mRNA (a type of genetic material) in bio...

Understanding Organ Transplant: Essential Patient Education Guide

This research paper examines the various methods of educating patients who are awaiting organ transplants. These educational measures aim to help patients understand the transplant process, its outcom...

Understanding Strongyloidiasis Infection After Organ Transplant

The research paper investigates a rare type of infection that can occur in patients who have undergone an organ transplant. The infection, called strongyloidiasis, is caused by a type of worm known as...

Understanding the Costs of Pig Organ Transplants Vs. Human Donors

This research paper looks into the costs of organ transplants from both human donors (allotransplants) and animal donors (xenotransplants). It finds that treating patients with severe organ failure wh...

Understanding Vaccine Mandates for Organ Transplant Recipients

This research paper discusses the viewpoint of a patient who has undergone an organ transplant on the topic of mandatory COVID-19 vaccinations. It's an exploration into how public policy related to th...

Using Suntrac to Assess Skin Cancer Risk in Heart and Lung Transplant

This research paper is about a tool called SUNTRAC that can help decide when to start checking for skin cancer in people who have had organ transplants. The study aimed to see if this tool would be us...

Xenotransplantation: a Promising Solution for Organ Shortages in Asia

There's a severe shortage of organs available for transplant worldwide. This is particularly true in Asia, where cultural factors lead to very low rates of organ donation. Simply changing organ donati...

Xenotransplantation: the Future of Organ Transplants From Animals

This research paper discusses a process called xenotransplantation, which involves transplanting organs from animals, specifically pigs, into humans. The study suggests that we might see formal clinic...

Xenotransplantation: Using Pig Organs for Human Transplants Explained

This research paper is about the potential use of animal organs for human transplant, a process known as xenotransplantation. Specifically, it looks at the use of pig organs for this purpose, as they ...

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