Our Summary

This research paper is exploring a new method for treating deep skin burns. Currently, the most common treatment is grafting skin from another part of the patient’s body onto the burn. However, this method can have complications, such as delayed healing and not having enough skin to graft.

One solution to this problem is to use a substitute for the skin graft, made from human skin that has had all its cells removed. This substitute, known as a human-derived acellular dermal matrix (HADM), has shown promising results. Unfortunately, it’s expensive and there’s a limited supply of skin donors.

This study looked at using skin from abdominal surgeries as a potential source for HADM. The skin was treated with a cheap and simple process, using salt and water, to remove the cells. The resulting product was shown to be safe and effective in laboratory tests.

The researchers conclude that this could be a viable way to produce HADM, providing a cheaper and more readily available option for treating deep skin burns. However, more research is needed to confirm these findings.

FAQs

  1. What is the current most common treatment for deep skin burns?
  2. What is a human-derived acellular dermal matrix (HADM) and how is it used in treating deep skin burns?
  3. How can skin from abdominal surgeries be used to treat deep skin burns according to the study?

Doctor’s Tip

A helpful tip a doctor might tell a patient about abdominoplasty is: If you consider having an abdominoplasty, or “tummy tuck”, remember that the excess skin removed during this procedure could potentially be used for medical advancements, such as the creation of human-derived acellular dermal matrix (HADM) for burn victims, as current research suggests. This fact may provide additional incentive or ease some concerns about undergoing the procedure.

Suitable For

Patients who are typically recommended for abdominoplasty, also known as a tummy tuck, include:

  1. Individuals who have excess skin and fat in the abdominal area that is resistant to diet and exercise.
  2. Patients who have undergone significant weight loss and have loose, sagging skin around the abdomen.
  3. Women who have had multiple pregnancies and have stretched abdominal muscles and skin.
  4. Individuals with weakened abdominal muscles due to aging or previous surgery.
  5. Patients with a hernia or other abdominal wall deformity that can be corrected during abdominoplasty.

It is important for patients considering abdominoplasty to have realistic expectations and be in good overall health before undergoing the procedure. As with any surgical procedure, there are risks and potential complications associated with abdominoplasty, so it is important to consult with a qualified plastic surgeon to determine if abdominoplasty is the right option for you.

Timeline

Before abdominoplasty:

  1. Patient consults with a plastic surgeon to discuss their goals and expectations for the surgery.
  2. Patient undergoes pre-operative evaluations and tests to ensure they are a suitable candidate for abdominoplasty.
  3. Patient receives instructions on pre-operative care, such as avoiding certain medications and preparing for the recovery period.

During abdominoplasty:

  1. Patient is put under general anesthesia.
  2. Surgeon makes incisions in the abdomen to remove excess skin and fat.
  3. Muscles may be tightened and repositioned.
  4. Skin is re-draped and incisions are closed with sutures.

After abdominoplasty:

  1. Patient wakes up from anesthesia in a recovery room.
  2. Patient is monitored for any complications or side effects.
  3. Patient may experience pain, swelling, and bruising in the abdominal area.
  4. Patient follows post-operative care instructions, including wearing compression garments and avoiding strenuous activities.
  5. Follow-up appointments with the surgeon are scheduled to monitor healing and address any concerns.
  6. Over time, swelling and bruising subside, and the final results of the surgery become more apparent.

Overall, the patient should see a flatter and more toned abdomen, with improved contours and a more youthful appearance.

What to Ask Your Doctor

  1. What are the potential risks and complications associated with abdominoplasty?
  2. How long is the recovery period after abdominoplasty?
  3. Will I need to follow any specific post-operative care instructions?
  4. Are there any alternative treatments or procedures that I should consider?
  5. How many abdominoplasty procedures have you performed, and what is your success rate?
  6. Can you show me before and after photos of patients who have undergone abdominoplasty?
  7. What is the cost of abdominoplasty, and will it be covered by my insurance?
  8. How will abdominoplasty affect my future pregnancies, if applicable?
  9. What can I expect in terms of scarring after abdominoplasty?
  10. Are there any lifestyle changes I should make before or after abdominoplasty to ensure optimal results?

Reference

Authors: Louri NA, Dey N, AlHasan RN, Abdulla SH, Elsakka M, Gulreez R, Darwish AH, Kadalmani B, Al Khalifa KBA. Journal: Tissue Eng Regen Med. 2022 Aug;19(4):727-738. doi: 10.1007/s13770-022-00439-3. Epub 2022 Mar 24. PMID: 35325403