Our Summary

This research paper analyzed the impact of COVID-19 on corneal donations and transplants in England. The study looked at data from all cornea donors and transplants from January 2020 to July 2021. It found that out of 4130 cornea transplant operations, 222 recipients later tested positive for COVID-19. However, only 2 of these patients died within a month of testing positive, and both had been diagnosed more than 30 days after their transplant. The study also found that 3 patients tested positive within two weeks of their transplant, but all 3 survived. Two of these patients had received corneas from donors who had been screened for COVID-19 and one from a donor who had tested negative two days before their death.

The research concluded that there is no evidence to suggest COVID-19 can be transmitted through cornea transplants. This is reassuring for the ongoing cornea transplant operations during the pandemic, and shows that the current safety and quality systems in place are effective.

FAQs

  1. What was the main finding of the research on cornea transplants and COVID-19 in England?
  2. Did the research find any evidence of COVID-19 being transmitted through cornea transplants?
  3. How many patients tested positive for COVID-19 within two weeks of their cornea transplant?

Doctor’s Tip

One helpful tip a doctor might give a patient about corneal transplant is to follow all post-operative care instructions carefully to reduce the risk of complications and ensure a successful outcome. This may include using prescribed eye drops, avoiding rubbing or touching the eyes, wearing protective eyewear, and attending follow-up appointments as scheduled. It is also important to communicate any changes or concerns with your healthcare provider promptly.

Suitable For

Patients who are typically recommended for corneal transplants include those with:

  1. Corneal scarring: Scarring of the cornea can occur due to infections, injuries, or previous surgeries, leading to vision impairment.

  2. Keratoconus: This is a progressive eye condition where the cornea becomes thin and cone-shaped, causing blurred and distorted vision.

  3. Fuchs’ dystrophy: This is a genetic condition where cells in the cornea’s inner layer deteriorate over time, leading to vision problems.

  4. Corneal ulcers: Severe infections or injuries to the cornea can cause ulcers that may require a transplant for proper healing.

  5. Corneal swelling: Conditions like endothelial dystrophy can cause the cornea to become swollen, leading to vision loss.

  6. Corneal degeneration: Degenerative conditions like keratitis or bullous keratopathy can result in thinning or clouding of the cornea, necessitating a transplant.

  7. Corneal trauma: Severe injuries to the cornea, such as chemical burns or lacerations, may require a transplant for proper healing and restoration of vision.

It is important for patients to undergo a thorough evaluation by an eye care specialist to determine if they are suitable candidates for a corneal transplant. Additionally, patients should discuss the potential risks and benefits of the procedure with their healthcare provider before deciding to undergo surgery.

Timeline

Before corneal transplant:

  1. Patient experiences vision problems, such as blurred vision or glare.
  2. Patient undergoes a comprehensive eye exam and consultation with an ophthalmologist.
  3. Ophthalmologist determines that a corneal transplant is necessary to improve vision.
  4. Patient is placed on a waiting list for a cornea donor match.

After corneal transplant:

  1. Patient undergoes the corneal transplant surgery, which typically takes 1-2 hours.
  2. Patient may experience discomfort and blurred vision immediately after surgery.
  3. Patient is prescribed medications to prevent infection and promote healing.
  4. Patient attends follow-up appointments to monitor healing and adjust medications as needed.
  5. Patient gradually experiences improved vision as the cornea heals and stitches are removed.
  6. Patient may need to wear glasses or contact lenses to achieve optimal vision after the transplant.

What to Ask Your Doctor

  1. Can COVID-19 be transmitted through a cornea transplant?
  2. What safety measures are in place to prevent the transmission of COVID-19 during a cornea transplant operation?
  3. How has the COVID-19 pandemic impacted the availability of cornea donors for transplant operations?
  4. Are there any specific precautions I should take before and after a cornea transplant operation to reduce the risk of contracting COVID-19?
  5. How will the COVID-19 pandemic affect the recovery process and follow-up care after a cornea transplant?
  6. Are there any additional risks or complications to consider regarding COVID-19 and a cornea transplant?
  7. How will the hospital or clinic ensure a safe environment for the cornea transplant operation in light of the COVID-19 pandemic?
  8. What should I do if I develop symptoms of COVID-19 after a cornea transplant operation?
  9. Are there any changes to the post-transplant medication regimen that I should be aware of due to COVID-19?
  10. What resources or support can I access for any concerns or questions about COVID-19 and my cornea transplant surgery?

Reference

Authors: Paulus U, Ushiro-Lumb I, Hopkinson C, Downward L, Shanmugaranjan S. Journal: BMJ Open Ophthalmol. 2022 Nov;7(Suppl 2):A3. doi: 10.1136/bmjophth-2022-EEBA.6. PMID: 37282687