Our Summary

This study looked at the effectiveness of a specific type of MRI-guided biopsy (a procedure where a small piece of tissue is taken from the body to examine it more closely) in diagnosing serious cases of prostate cancer. Over a three-year period, 125 patients underwent this procedure. The results showed that for patients who had suspicious or unclear MRI results, this type of biopsy was quite effective in detecting serious prostate cancer. However, the detection rate was lower for those with less clear results. The study also found that this procedure was effective in patients who had previously tested negative for cancer, as well as those who were having their first biopsy. Importantly, there were few complications associated with the biopsy, suggesting that it is a safe procedure. The researchers concluded that this type of MRI-guided biopsy could be a useful tool in both initial and follow-up testing for prostate cancer.

FAQs

  1. How effective is the MRI-guided biopsy in diagnosing serious cases of prostate cancer?
  2. Is the MRI-guided biopsy a safe procedure and are there any associated complications?
  3. Can this MRI-guided biopsy be useful for both initial and follow-up testing for prostate cancer?

Doctor’s Tip

One helpful tip a doctor might tell a patient about prostate biopsy is to discuss any concerns or questions they may have before the procedure. It is important for the patient to understand the purpose of the biopsy, the potential risks and benefits, and what to expect during and after the procedure. Additionally, the doctor may recommend avoiding certain medications or supplements that could increase the risk of bleeding during the biopsy. It is also important for the patient to follow any pre-procedure instructions provided by the doctor to ensure the biopsy is conducted safely and effectively.

Suitable For

Patients who are typically recommended for a prostate biopsy include:

  1. Men with elevated prostate-specific antigen (PSA) levels: High levels of PSA in the blood may indicate the presence of prostate cancer.

  2. Men with abnormal digital rectal exam (DRE) findings: Abnormalities in the prostate gland detected during a physical exam may warrant further investigation.

  3. Men with a family history of prostate cancer: Individuals with a family history of the disease are at a higher risk and may benefit from regular screening and biopsies.

  4. Men with suspicious or unclear MRI results: Patients with MRI findings that suggest the presence of prostate cancer may be recommended for a biopsy to confirm the diagnosis.

  5. Men with prior negative biopsy results: Patients who have previously tested negative for cancer but continue to have symptoms or abnormal test results may be advised to undergo a repeat biopsy.

  6. Men undergoing active surveillance for low-risk prostate cancer: Patients who are being monitored for early-stage, low-grade prostate cancer may undergo periodic biopsies to monitor disease progression.

Overall, the decision to recommend a prostate biopsy is based on a combination of factors, including PSA levels, DRE findings, family history, and imaging results. It is important for patients to discuss the risks and benefits of the procedure with their healthcare provider to make an informed decision.

Timeline

Before the prostate biopsy:

  1. Patient meets with their healthcare provider to discuss symptoms or abnormal test results that may indicate prostate cancer.
  2. Patient may undergo a digital rectal exam (DRE) to check for any abnormalities in the prostate gland.
  3. Patient may undergo a prostate-specific antigen (PSA) blood test to measure levels of a protein produced by the prostate gland that can indicate the presence of cancer.
  4. Patient may undergo a transrectal ultrasound (TRUS) to examine the prostate gland more closely.
  5. If abnormalities are found, patient may be recommended for a prostate biopsy.

After the prostate biopsy:

  1. Patient may experience discomfort or pain in the prostate area for a few days after the procedure.
  2. Patient may notice blood in their urine or semen for a few days after the biopsy.
  3. Patient may be advised to avoid heavy lifting or strenuous activities for a few days to allow the prostate to heal.
  4. Patient will wait for the results of the biopsy, which can take a few days to a week to come back.
  5. Depending on the results, patient may undergo further testing or treatment for prostate cancer if necessary.

What to Ask Your Doctor

  1. What is the purpose of a prostate biopsy?
  2. How is a prostate biopsy performed?
  3. How long does the procedure take and what can I expect during and after the biopsy?
  4. What are the potential risks and complications associated with a prostate biopsy?
  5. How accurate is a prostate biopsy in detecting prostate cancer?
  6. What are the different types of prostate biopsies available and which one is recommended for me?
  7. Will I need to do any special preparation before the biopsy?
  8. How soon will I receive the results of the biopsy?
  9. What are the next steps if the biopsy results show signs of prostate cancer?
  10. Are there any alternative tests or procedures that can be considered instead of a prostate biopsy?

Reference

Authors: Furrer MA, Hong A, Wetherell D, Heinze SB, Simkin P, Chow K, Lawrentschuk N, Zargar H. Journal: ANZ J Surg. 2022 Jun;92(6):1486-1491. doi: 10.1111/ans.17713. Epub 2022 Apr 28. PMID: 35482421