Our Summary

This research paper reviews and compares two non-surgical tests used to detect breast cancer in women with suspicious lesions: fine needle aspiration cytology (FNAC) and core needle biopsy (CNB). The researchers reviewed previous studies and found that both tests are effective in detecting breast cancer. However, CNB was found to be more sensitive, meaning it was better at correctly identifying people who have the disease. On the other hand, the two tests had similar specificity, meaning they were equally effective at correctly identifying people who do not have the disease. The researchers also noted that both tests were more sensitive when used on palpable (able to be felt) lesions compared to non-palpable ones. They concluded that while both tests perform well, CNB is more sensitive, and FNAC could still be the first choice for evaluating non-palpable breast lesions.

FAQs

  1. What are the two non-surgical tests used to detect breast cancer discussed in the research paper?
  2. Which of the two tests, FNAC or CNB, was found to be more sensitive in detecting breast cancer?
  3. Are FNAC and CNB more sensitive when used on palpable or non-palpable lesions?

Doctor’s Tip

It is important to follow the recommendations of your healthcare provider and have regular breast screenings, such as mammograms, to detect any abnormalities early on. If a breast biopsy is recommended, it is important to follow through with the procedure as it can provide valuable information about the presence of cancer or other conditions in the breast tissue. It is also important to discuss any concerns or questions you may have with your healthcare provider before and after the biopsy procedure.

Suitable For

Patients who are typically recommended for a breast biopsy include those with suspicious breast lumps or masses, abnormal findings on a mammogram or other imaging tests, nipple discharge, breast skin changes, or a family history of breast cancer. Additionally, patients with a personal history of breast cancer or other risk factors for the disease may also be recommended for a breast biopsy. It is important for healthcare providers to carefully evaluate each individual case and determine the most appropriate course of action for each patient.

Timeline

  • Initial screening: A patient may undergo a routine mammogram or clinical breast exam that reveals a suspicious lesion in the breast.

  • Consultation with a healthcare provider: The patient meets with a healthcare provider who recommends a breast biopsy to further evaluate the suspicious lesion.

  • Pre-biopsy preparation: The patient may undergo additional imaging tests, such as an ultrasound or MRI, to guide the biopsy procedure. They may also be instructed to avoid certain medications, such as blood thinners, leading up to the biopsy.

  • Biopsy procedure: The patient undergoes either a fine needle aspiration cytology (FNAC) or core needle biopsy (CNB) to obtain a tissue sample from the suspicious lesion. Local anesthesia is usually administered to numb the area before the procedure.

  • Post-biopsy recovery: The patient may experience some discomfort or bruising at the biopsy site following the procedure. They are typically able to resume normal activities shortly after the biopsy.

  • Biopsy results: The tissue sample obtained during the biopsy is examined by a pathologist to determine if cancer is present. The patient receives the results from their healthcare provider, who discusses the next steps in their treatment plan if cancer is detected.

  • Follow-up care: Depending on the biopsy results, the patient may undergo further imaging tests or additional procedures to determine the extent of the cancer and develop a treatment plan. This may include surgery, chemotherapy, radiation therapy, or other treatments as recommended by their healthcare team.

What to Ask Your Doctor

  1. What type of breast biopsy procedure do you recommend for me? (e.g. fine needle aspiration cytology, core needle biopsy)
  2. How will the biopsy be performed and what can I expect during the procedure?
  3. Will I need to stop taking any medications or supplements before the biopsy?
  4. How long will it take to get the results of the biopsy?
  5. What are the potential risks or complications associated with the biopsy procedure?
  6. What will happen if the biopsy results come back positive for cancer?
  7. Are there any alternative tests or procedures that could be done instead of a biopsy?
  8. How will the biopsy results impact my treatment plan moving forward?
  9. Will I need to follow up with any additional tests or appointments after the biopsy?
  10. Are there any lifestyle changes or precautions I should take before or after the biopsy procedure?

Reference

Authors: Wang M, He X, Chang Y, Sun G, Thabane L. Journal: Breast. 2017 Feb;31:157-166. doi: 10.1016/j.breast.2016.11.009. Epub 2016 Nov 17. PMID: 27866091