Our Summary

This study investigated changes in the brain’s hunger and satisfaction centers in seriously overweight patients before and after weight-loss surgery. Using a special type of imaging called diffusion tensor imaging (DTI), researchers looked at the diffusion of water in these brain areas. They found significant differences in the measures (mean diffusivity and fractional anisotropy) before and after the surgery. The changes may be due to temporary inflammation in the brain’s hunger and satisfaction centers reversing, and structural recovery in these areas. This means that the surgery not only helps patients lose weight, but also causes changes in the brain that could potentially help them maintain their weight loss.

FAQs

  1. What type of imaging was used in this study to investigate changes in the brain’s hunger and satisfaction centers?
  2. What changes were found in the brain’s hunger and satisfaction centers after weight-loss surgery?
  3. How can weight-loss surgery potentially help patients maintain their weight loss?

Doctor’s Tip

One helpful tip a doctor might tell a patient about brain surgery is to follow post-operative care instructions carefully. This may include taking prescribed medications, attending follow-up appointments, following a specific diet or exercise plan, and avoiding certain activities that could put strain on the surgical site. By following these instructions, patients can help ensure a successful recovery and optimize the benefits of the surgery.

Suitable For

Patients who are seriously overweight and have not been successful with other weight loss methods may be recommended for weight-loss surgery, such as gastric bypass or gastric sleeve surgery. These patients typically have a body mass index (BMI) of 40 or higher, or a BMI of 35 or higher with obesity-related health conditions such as type 2 diabetes or high blood pressure.

Additionally, patients who have certain brain tumors, aneurysms, arteriovenous malformations, or other neurological conditions that require surgical intervention may also be recommended for brain surgery. These patients may experience symptoms such as headaches, seizures, weakness, numbness, or changes in cognition that are not responding to other treatments.

It is important for patients considering brain surgery to undergo a comprehensive evaluation by a neurosurgeon and other specialists to determine if they are good candidates for surgery and to discuss the potential risks and benefits of the procedure.

Timeline

Before brain surgery:

  1. Patient consults with a neurosurgeon to discuss the need for surgery and potential risks and benefits.
  2. Patient undergoes pre-operative tests such as MRI or CT scans to assess the condition of the brain.
  3. Patient may undergo counseling or therapy to prepare mentally and emotionally for the surgery.
  4. Patient may need to make lifestyle changes or take medications to optimize their health before surgery.

After brain surgery:

  1. Patient is closely monitored in the intensive care unit immediately after surgery to ensure no complications arise.
  2. Patient may experience pain, swelling, and discomfort at the surgical site.
  3. Patient may need to stay in the hospital for a few days to recover and receive post-operative care.
  4. Patient may need physical therapy or rehabilitation to regain strength, coordination, and function.
  5. Patient will have follow-up appointments with their neurosurgeon to monitor their recovery and address any concerns or complications.

What to Ask Your Doctor

  1. What specific type of brain surgery will I be undergoing?
  2. What are the potential risks and complications associated with this surgery?
  3. How long will the recovery process be and what can I expect during this time?
  4. Will I need any additional treatments or therapies after the surgery?
  5. How will this surgery affect my brain function and overall cognitive abilities?
  6. What lifestyle changes will I need to make post-surgery to optimize my results?
  7. Will I need to follow a specific diet or exercise regimen after the surgery?
  8. How often will I need to follow up with you or a specialist after the surgery?
  9. Are there any long-term effects or risks associated with this surgery that I should be aware of?
  10. Can you explain the findings of this study and how they relate to my specific situation?

Reference

Authors: Yurtsever I, Atasoy B, Bozkurt S, Yıldız GB, Balsak S, Yabul F, Donmez Z, Selvitop R, Karaman O, Toluk O, Alkan A. Journal: Ir J Med Sci. 2024 Feb;193(1):191-197. doi: 10.1007/s11845-023-03389-4. Epub 2023 May 25. PMID: 37231150