Our Summary

This research paper review looks at the use of platelet-rich plasma (PRP) in oral and face surgery. PRP is a substance derived from blood that promotes healing, and several types are used in clinical practice. One key difference between these types is whether or not they contain white blood cells (leukocytes). This review found that there’s not much evidence on how the composition of PRP impacts its effectiveness. The authors aim to fill this gap by looking at existing research on the effectiveness of PRP in oral and face surgery, with a focus on how its composition plays a role.

The review found that using PRP in these types of surgeries can potentially improve the regeneration of both soft and hard tissue. The effectiveness of PRP, however, seems to differ based on its composition and how it’s used. In particular, PRP without leukocytes has shown more reliable benefits in preserving alveolar ridge (the bone in the mouth that holds the teeth), managing complications after tooth extraction, enhancing bone growth, and treating temporomandibular joint disorders (issues related to the jaw joint). The authors conclude that the composition of PRP and how it’s prepared should be carefully evaluated when considering its use in surgery.

FAQs

  1. What is the role of platelet-rich plasma (PRP) in oral and maxillofacial surgery?
  2. How does the composition of PRP influence its efficacy in oral and maxillofacial surgery?
  3. What are the potential benefits of PRP in managing post-extraction complications, bone augmentation, and temporomandibular joint disorders?

Doctor’s Tip

A helpful tip a doctor might tell a patient about maxillofacial surgery is to consider the use of platelet-rich plasma (PRP) in their treatment plan. PRP has been shown to improve soft- and hard-tissue regeneration in oral and maxillofacial surgery, particularly when the PRP does not contain leukocytes. Patients should discuss with their doctor the composition and methodology used to prepare the PRP, as this can impact the efficacy of the treatment.

Suitable For

Patients who may benefit from maxillofacial surgery include those with:

  1. Facial trauma: Patients who have suffered facial injuries, such as fractures, dislocations, or soft tissue injuries, may require maxillofacial surgery to repair and reconstruct the affected areas.

  2. Corrective jaw surgery: Patients with misaligned jaws, such as underbites, overbites, or crossbites, may undergo maxillofacial surgery to correct the alignment of the jaw and improve function and aesthetics.

  3. Temporomandibular joint (TMJ) disorders: Patients with TMJ disorders, such as pain, clicking, or difficulty with jaw movement, may benefit from maxillofacial surgery to address the underlying issues causing the dysfunction.

  4. Cleft lip and palate: Patients born with cleft lip and palate deformities may require maxillofacial surgery to repair and reconstruct the affected areas for improved function and aesthetics.

  5. Sleep apnea: Patients with obstructive sleep apnea, a condition characterized by breathing pauses during sleep, may undergo maxillofacial surgery to improve airway patency and reduce symptoms.

  6. Tumors and cysts: Patients with tumors or cysts in the oral and maxillofacial region may require surgery to remove the abnormal growth and restore normal function and appearance.

  7. Dental implants: Patients who require dental implants for missing teeth may undergo maxillofacial surgery to prepare the jawbone for implant placement and ensure optimal support and stability.

Overall, maxillofacial surgery is recommended for patients with a variety of conditions affecting the oral and facial structures, with the goal of improving function, aesthetics, and quality of life.

Timeline

Before maxillofacial surgery:

  • Patient consults with oral and maxillofacial surgeon to discuss treatment options
  • Pre-operative assessments and tests are conducted to evaluate the patient’s health status
  • Surgical plan is developed based on the patient’s individual needs
  • Patient receives instructions on pre-operative care and what to expect during and after surgery

After maxillofacial surgery:

  • Patient undergoes surgery under anesthesia
  • Post-operative care and instructions are provided to the patient, including pain management and wound care
  • Follow-up appointments are scheduled to monitor the healing process and address any concerns
  • Patient may experience swelling, bruising, and discomfort in the days following surgery
  • Over time, the patient’s tissues and bones heal and regenerate, with the help of treatments like platelet-rich plasma (PRP) to enhance the healing process

Overall, the timeline for a patient before and after maxillofacial surgery can vary depending on the specific procedure and individual circumstances, but the goal is to achieve optimal outcomes in terms of function and aesthetics.

What to Ask Your Doctor

  1. What specific benefits can I expect from using platelet-rich plasma (PRP) in my oral and maxillofacial surgery procedure?
  2. How is the PRP prepared for use in my surgery, and what is the composition of the PRP being used?
  3. Are there any potential risks or side effects associated with using PRP in my surgery?
  4. How will the use of PRP impact my recovery time and overall healing process?
  5. What alternatives to PRP are available for my specific procedure, and how does PRP compare in terms of efficacy and outcomes?
  6. Can you provide any specific studies or research that support the use of PRP in oral and maxillofacial surgery?
  7. How will the cost of incorporating PRP into my surgery impact my overall treatment plan and financial considerations?
  8. Will I need multiple PRP treatments or follow-up appointments after my surgery, and if so, what is the recommended schedule for these treatments?
  9. How long has PRP been used in oral and maxillofacial surgery, and what is the success rate or patient satisfaction rate for those who have used PRP in similar procedures?
  10. Are there any specific lifestyle changes or post-operative care instructions I should follow to optimize the benefits of using PRP in my surgery?

Reference

Authors: Anitua E, Fernández-de-Retana S, Alkhraisat MH. Journal: Platelets. 2021 Feb 17;32(2):174-182. doi: 10.1080/09537104.2020.1856361. Epub 2020 Dec 22. PMID: 33350883