Our Summary

This study looked at 48 women who had a specific genetic mutation (BRCA 1 and/or 2) that can increase the risk of ovarian cancer. These women had undergone a preventative surgery to remove their fallopian tubes and ovaries to reduce this risk. The researchers were checking to see how many of these women developed a type of pre-cancer (STIC) or high-grade ovarian cancer (HGSOC) after the surgery. They found that one woman (2% of the group) developed STIC, and another woman (also 2% of the group) was found to have hidden ovarian cancer after her surgery. Another woman (again, 2% of the group) developed peritoneal cancer (a rare cancer that develops in the lining of the abdomen) 57 months after her surgery. The main takeaway is that even after having the preventative surgery, there is still a risk of developing these types of cancer, so close monitoring is important to catch any issues early and treat them effectively.

FAQs

  1. What is the percentage of women in the study who developed STIC or HGSOC after undergoing a preventative surgery?
  2. Can peritoneal cancer develop after a preventative surgery to remove fallopian tubes and ovaries?
  3. Why is close monitoring important even after having a preventative surgery for ovarian cancer?

Doctor’s Tip

It is important to continue regular check-ups and screenings with your healthcare provider after a salpingo-oophorectomy to monitor for any signs of cancer or other health concerns. Be sure to communicate any changes or symptoms you may experience to your doctor promptly.

Suitable For

Patients who are typically recommended salpingo-oophorectomy are those who have a high risk of developing ovarian cancer, such as those with a genetic mutation like BRCA 1 and/or 2. This surgery is often recommended as a preventative measure to reduce the risk of developing ovarian cancer in these high-risk individuals. Close monitoring after the surgery is also important to catch any potential issues early and treat them effectively.

Timeline

Before the salpingo-oophorectomy:

  • Patient undergoes genetic testing to determine if they have a mutation in the BRCA 1 and/or 2 genes
  • Patient receives counseling on the risks and benefits of undergoing a preventative surgery
  • Patient decides to undergo the surgery to reduce their risk of ovarian cancer
  • Surgery is scheduled and pre-operative preparations are made

After the salpingo-oophorectomy:

  • Patient undergoes the surgery to remove their fallopian tubes and ovaries
  • Patient recovers in the hospital for a few days post-surgery
  • Patient may experience side effects such as pain, fatigue, and hormonal changes
  • Patient is monitored closely for any signs of complications or cancer development
  • Follow-up appointments are scheduled to monitor the patient’s health and well-being
  • Some patients may require hormone replacement therapy after the surgery to manage menopausal symptoms
  • Patient is advised to continue with regular screenings and check-ups to monitor for any signs of cancer development

Overall, the timeline for a patient before and after a salpingo-oophorectomy involves careful consideration of the risks and benefits of the surgery, close monitoring for any potential complications or cancer development, and ongoing follow-up care to ensure the patient’s health and well-being.

What to Ask Your Doctor

  1. What are the risks and benefits of undergoing a salpingo-oophorectomy for me specifically?
  2. How will this surgery affect my hormone levels and menopausal symptoms?
  3. How often will I need to have follow-up screenings or tests after the surgery?
  4. Are there any alternative options to reduce my risk of ovarian cancer?
  5. How will this surgery impact my fertility, and are there any options for preserving fertility before the surgery?
  6. What is the likelihood of developing other types of cancer, such as peritoneal cancer, after the surgery?
  7. Are there any long-term side effects or complications I should be aware of?
  8. How will this surgery impact my overall health and quality of life?
  9. Are there any lifestyle changes or preventative measures I can take to reduce my risk of cancer after the surgery?
  10. How will my medical history, family history, and genetic mutations (if applicable) impact the outcome of this surgery?

Reference

Authors: Abay M, Ozgen L, Yalcin Y, Ozerkan K. Journal: J Gynecol Obstet Hum Reprod. 2023 Oct;52(8):102642. doi: 10.1016/j.jogoh.2023.102642. Epub 2023 Aug 11. PMID: 37573025