Our Summary

This research paper explores the role of a hormone called ghrelin, which is produced in a part of the stomach known as the gastric fundus, in controlling blood sugar levels. The researchers looked at whether removing the gastric fundus, which is a common part of some weight loss surgeries, could help improve blood sugar control. They reviewed a number of studies and found that after the gastric fundus is removed, ghrelin levels often decrease, which might help improve blood sugar levels before any significant weight loss occurs. However, there isn’t much long-term data on this topic yet. The researchers conclude that while early indications suggest ghrelin could play a role in blood sugar regulation, more research is needed to fully understand this relationship.

FAQs

  1. What is the role of the hormone ghrelin in controlling blood sugar levels?
  2. How could removing the gastric fundus potentially improve blood sugar control?
  3. Is there any long-term data on the relationship between ghrelin and blood sugar regulation?

Doctor’s Tip

A helpful tip a doctor might tell a patient about gastric sleeve surgery is to follow a healthy diet and exercise regimen post-surgery to maximize weight loss and improve overall health outcomes. It is also important to attend regular follow-up appointments with your healthcare provider to monitor progress and address any issues that may arise. Additionally, it is important to stay hydrated and take any prescribed medications as directed to ensure a successful recovery.

Suitable For

Patients who are typically recommended for gastric sleeve surgery are those who have a body mass index (BMI) of 40 or higher, or a BMI of 35 or higher with obesity-related health conditions such as type 2 diabetes, high blood pressure, or sleep apnea. Additionally, patients who have tried and failed to lose weight through other methods such as diet and exercise may also be recommended for gastric sleeve surgery. It is important for patients to undergo a thorough evaluation by a healthcare provider to determine if they are a suitable candidate for this type of weight loss surgery.

Timeline

Before Gastric Sleeve Surgery:

  • Patient undergoes a series of consultations with healthcare providers to discuss the risks and benefits of the surgery, as well as the expected outcomes.
  • Patient may be required to undergo various tests and evaluations to determine if they are a suitable candidate for gastric sleeve surgery.
  • Patient may be asked to make lifestyle changes, such as following a specific diet or exercise plan, in preparation for the surgery.

After Gastric Sleeve Surgery:

  • Patient typically stays in the hospital for a few days after the surgery for monitoring and recovery.
  • Patient is advised to follow a strict diet plan, typically starting with liquids and gradually transitioning to solid foods over time.
  • Patient is encouraged to engage in regular physical activity to support weight loss and overall health.
  • Patient attends regular follow-up appointments with their healthcare provider to monitor progress and address any concerns or complications.
  • Over time, patient may experience significant weight loss and improvements in various health markers, such as blood sugar levels, blood pressure, and cholesterol levels.

Overall, the timeline for a patient before and after gastric sleeve surgery involves careful preparation, immediate post-operative care, and ongoing support and monitoring to ensure successful outcomes and long-term health benefits.

What to Ask Your Doctor

  1. How will removing the gastric fundus through the gastric sleeve surgery affect my levels of ghrelin?

  2. Will lowering ghrelin levels through the gastric sleeve surgery help improve my blood sugar control?

  3. Are there any potential risks or side effects associated with changes in ghrelin levels after gastric sleeve surgery?

  4. How long will it take to see improvements in blood sugar control after undergoing the gastric sleeve surgery?

  5. Are there any additional lifestyle changes or medications I should consider to optimize blood sugar control after gastric sleeve surgery?

  6. Are there any long-term studies or data available on the relationship between ghrelin levels and blood sugar control following gastric sleeve surgery?

  7. How often should I have my blood sugar levels monitored after the gastric sleeve surgery?

  8. Will I need to make any adjustments to my diabetes medications or insulin dosages after the gastric sleeve surgery?

  9. What support or resources are available to help me manage my blood sugar levels effectively after the gastric sleeve surgery?

  10. Are there any dietary recommendations or restrictions I should follow to support blood sugar control after the gastric sleeve surgery?

Reference

Authors: Kehagias D, Georgopoulos N, Habeos I, Lampropoulos C, Mulita F, Kehagias I. Journal: Hormones (Athens). 2023 Jun;22(2):151-163. doi: 10.1007/s42000-023-00429-7. Epub 2023 Jan 27. PMID: 36705877