Our Summary

This research paper looks at a type of surgery called open partial horizontal laryngectomy (OPHL) which is used for treating advanced laryngeal (throat) cancer. The study aimed to understand how well this surgery worked for different stages of cancer and what factors could influence a patient’s survival rate.

The researchers looked at the records of 170 patients who had this surgery between 2005 and 2018. They found that the survival rate after five years was roughly 80% for early-stage cancer (T2) and slightly less for later stages (T3 and T4). They also found that the likelihood of surviving was reduced if the cancer had spread to the back of the throat, if it had invaded the nerves, or if the patient had N status (which means the cancer had spread to nearby lymph nodes).

In conclusion, the study showed that OPHL can be a successful treatment for advanced laryngeal cancer. However, it’s important to carefully select patients for this surgery based on how advanced their cancer is and other individual factors.

FAQs

  1. What is open partial horizontal laryngectomy (OPHL)?
  2. How effective is OPHL in treating advanced laryngeal cancer?
  3. What factors could influence a patient’s survival rate after OPHL?

Doctor’s Tip

A doctor might tell a patient undergoing a laryngectomy to follow their post-operative care instructions carefully, including maintaining good oral hygiene, avoiding smoking and alcohol, and attending follow-up appointments. They may also advise the patient to communicate any changes in their voice or breathing to their healthcare provider promptly.

Suitable For

Patients who are typically recommended for laryngectomy are those with advanced laryngeal cancer that has not responded to other treatments such as radiation therapy or chemotherapy. Additionally, patients who have tumors that are too large to be removed with less invasive procedures may also be recommended for laryngectomy. Patients with cancer that has spread to nearby lymph nodes or nerves may also be candidates for this surgery. Overall, the decision to recommend laryngectomy to a patient is based on the individual’s specific cancer stage, location, and overall health status.

Timeline

Before laryngectomy:

  • Patient experiences symptoms of laryngeal cancer such as hoarseness, difficulty swallowing, ear pain, or a lump in the neck
  • Patient undergoes diagnostic tests such as a biopsy, imaging scans, and laryngoscopy to confirm the diagnosis
  • Patient discusses treatment options with their healthcare team, which may include surgery, radiation therapy, chemotherapy, or a combination of these
  • Patient undergoes preoperative preparation, which may include counseling, education on postoperative care, and nutritional support

After laryngectomy:

  • Patient undergoes laryngectomy surgery, where part or all of the larynx is removed to treat the cancer
  • Patient may experience temporary or permanent changes in speech, breathing, and swallowing post-surgery
  • Patient undergoes rehabilitation to learn how to communicate using alternative methods such as speech therapy, tracheoesophageal puncture, or electronic speech devices
  • Patient may need to adjust to lifestyle changes such as dietary modifications, avoiding smoking and alcohol, and regular follow-up appointments for monitoring and support
  • Patient may experience emotional and psychological challenges such as grief, anxiety, or depression, and may benefit from counseling or support groups

What to Ask Your Doctor

Questions a patient should ask their doctor about laryngectomy may include:

  1. What stage is my laryngeal cancer and is open partial horizontal laryngectomy a suitable treatment option for me?
  2. What are the potential risks and complications associated with this surgery?
  3. How will my voice be affected after the laryngectomy and what speech rehabilitation options are available to me?
  4. What is the expected recovery time and what kind of follow-up care will I need after the surgery?
  5. How will my ability to swallow be affected and what dietary changes may be necessary?
  6. What are the chances of the cancer recurring after the surgery and what steps can I take to reduce this risk?
  7. Will I need additional treatments such as radiation or chemotherapy after the laryngectomy?
  8. How will the surgery impact my quality of life and what support services are available to help me cope with any emotional or physical changes?
  9. Are there any clinical trials or experimental treatments that I may be eligible for?
  10. What is the long-term outlook for patients who undergo open partial horizontal laryngectomy for advanced laryngeal cancer?

Reference

Authors: de Vincentiis M, Greco A, Campo F, Candelori F, Ralli M, Di Traglia M, Colizza A, Cambria F, Zocchi J, Manciocco V, Spriano G, Pellini R. Journal: Eur Arch Otorhinolaryngol. 2022 Jun;279(6):2997-3004. doi: 10.1007/s00405-021-07238-x. Epub 2022 Jan 3. PMID: 34978589