Our Summary

This study looked at the use of a certain type of biopsy (tissue sample collection) for diagnosing lung cancer. The biopsy method is called CT-guided core-needle biopsy, which uses imagery from a CT scan to guide a needle to the right area to collect a tissue sample.

The researchers looked at 350 biopsies that were performed between 2017 and 2022. They found that this method was very accurate (around 99% accurate) and sensitive (90% effective at correctly identifying people with lung cancer). It also had a 100% positive predictive value, meaning that if the biopsy suggested cancer, it was always correct.

The method was also safe, with only three patients experiencing major complications. However, the study found that certain factors, like emphysema and longer distances to the pleura (the membrane that covers the lungs), were associated with minor complications like pneumothorax (collapsed lung) or bleeding in the lungs.

The biopsies also provided enough tissue for further advanced tests that can look at things like genetic sequencing. This suggests that this type of biopsy could be a very useful tool for diagnosing lung cancer and guiding further treatment.

FAQs

  1. What is CT-guided core-needle biopsy and how is it used for diagnosing lung cancer?
  2. How accurate and safe is the CT-guided core-needle biopsy method according to the study?
  3. What complications were associated with the CT-guided core-needle biopsy method and which factors influenced their occurrence?

Doctor’s Tip

One helpful tip a doctor might tell a patient about lung biopsy is to follow all pre-procedure instructions carefully, such as fasting before the procedure and informing the medical team of any medications being taken. It is also important to discuss any concerns or questions with the doctor beforehand to ensure a smooth and successful procedure. Additionally, it is important to follow post-procedure care instructions, such as resting and avoiding strenuous activities for a period of time to allow for proper healing.

Suitable For

Patients who are typically recommended for a lung biopsy include those with suspicious lung nodules or masses that may be indicative of lung cancer. Other patients who may benefit from a lung biopsy include those with unexplained lung infections, abnormal chest x-rays or CT scans, or those who are not responding to treatment for a known lung condition. Additionally, patients with a history of smoking or exposure to environmental toxins may be recommended for a lung biopsy to rule out or confirm lung cancer.

Timeline

Before the lung biopsy:

  1. Patient presents with symptoms such as persistent cough, chest pain, shortness of breath, or coughing up blood.
  2. Patient undergoes imaging tests such as chest x-ray or CT scan to identify abnormal growth in the lungs.
  3. Patient may undergo other diagnostic tests such as bronchoscopy or sputum cytology to further investigate the abnormal growth.
  4. After discussion with a healthcare provider, a decision is made to proceed with a lung biopsy.

During the lung biopsy:

  1. Patient is prepared for the procedure and given anesthesia or sedation for comfort.
  2. A CT scan is used to guide a needle to the area of concern in the lung.
  3. Tissue samples are collected using the needle, and the procedure is monitored for any complications.
  4. The tissue samples are sent to a lab for analysis to determine if cancer cells are present.

After the lung biopsy:

  1. Patient may experience mild pain or discomfort at the biopsy site, which can be managed with pain medication.
  2. Results from the biopsy are typically available within a few days to a week.
  3. If cancer is confirmed, further tests may be conducted to determine the stage and extent of the cancer.
  4. Treatment options, such as surgery, chemotherapy, or radiation therapy, are discussed with the patient.
  5. Follow-up appointments are scheduled to monitor the patient’s progress and response to treatment.

What to Ask Your Doctor

  1. What is the purpose of a lung biopsy in my case?
  2. How will the CT-guided core-needle biopsy be performed?
  3. What are the risks and potential complications associated with this type of biopsy?
  4. How accurate and reliable is this method for diagnosing lung cancer?
  5. Will the biopsy provide enough tissue for further testing, such as genetic sequencing?
  6. Are there any specific factors or conditions that may increase the risk of complications during or after the biopsy?
  7. How soon will I receive the results of the biopsy?
  8. What are the potential treatment options depending on the biopsy results?
  9. Are there any alternative diagnostic tests or biopsy methods that could be considered in my case?
  10. What should I expect in terms of recovery and follow-up care after the biopsy procedure?

Reference

Authors: Baratella E, Cernic S, Minelli P, Furlan G, Crimì F, Rocco S, Ruaro B, Cova MA. Journal: Tomography. 2022 Nov 25;8(6):2828-2838. doi: 10.3390/tomography8060236. PMID: 36548528